Guthriesville - Horseshoe Pike

Discover personalized primary care right in your neighborhood. 
Guthriesville - Horseshoe Pike
1229 Horseshoe Pike
Downingtown, Pennsylvania 19335

View on Google Maps
Guthriesville horseshoe pike building


A primary care provider’s specialty isn’t treating your disease, it’s treating you. Knowing the details of your health is how we stay in tune with your overall physical and mental wellness. As an LGBTQ Inclusive Care practice, our providers have undergone additional training to understand the unique needs of the community and to provide highly competent care.

We are in Downingtown on Route 322 (Horseshoe Pike) in the village of Guthriesville. We are in the Brandywine Village Shopping Center (Crop's Market). Free parking is available.


Our Guthriesville location in Downingtown offers primary and specialty care aimed at keeping our patients healthy through preventive care and management of their health condition

Primary Care

Experience comprehensive and compassionate primary care and family medicine services at Main Line Health, delivering advanced care for your overall well-being.

Senior Health (Geriatric Medicine)

Main Line Health experts provide specialized care so adults of all ages can maintain their independence and live life to the fullest.

LGBTQ+ Inclusive Care

Receive inclusive LGBTQ+ medical care at Main Line Health in a compassionate and welcoming space at locations in the Philadelphia region.

Billing and insurance

We don’t want you to feel stressed about payment after you go home. Learn more about price transparency, itemization or requesting an estimate.

Our Practices

well ahead logo Content you want, delivered to your inbox

Want to get the latest health and wellness articles delivered right to your inbox? 

Subscribe to the Well Ahead Newsletter.

Man smiling looking at his phone